DDePICt Research Program

Informing the practice of donation after circulatory determination of death in Canada

The Death Prediction and Physiology after Removal of Therapy study aims to provide information about the physiology of death after withdrawal of life sustaining therapy in the ICU...

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DePPaRT Study Updates - July 2016 

7/27/2016

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The DePPaRT study is now just 15 patient enrolments away from our 250 patient halfway point!! Total enrolment is now at 235 patients. 

Other updates this month include:
  • Coordinators Marlene Santos and Orla Smith at St. Michael’s hospital have done a great job with enrolment this month with 3 patients enrolled – they are tied with our site in Prague for the highest number of enrolments this month (the first for a Canadian site!)
  • Coordinators Nicole Marinoff and Jane Wang overcame issues with their waveform capture software to enrol their first 2 patients at Sunnybrook!
  • Coordinator Lori Hand at Hamilton has officially passed the 20 patient mark!
  • Coordinator Josie Campisi at the Montreal General has enrolled her first patient since starting with the study
  • The study team at our London site has been asking families to add EEG and trans-cranial doppler measurements during withdrawal of life sustaining therapies – so far they have added EEGs to 5 patients, 3 of which have also had dopplers
  • The DePPaRT central team is busy writing a proposal for a 2016 CIHR meeting grant to bring together our international collaborators

A more detailed breakdown of our enrolment numbers is available on our study progress page.

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DePPaRT-Neuro: Abstract Presented at Canadian Neurological Sciences Congress in Quebec City

7/12/2016

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As an add-on to the DePPaRT study, researchers at the London Health Sciences Centre in London, Ontario have provided families the option to consent not just to existing clinical monitoring, but also to add an EEG machine to monitor what happens to the brain during the process of withdrawal of life sustaining therapies and after death. So far, several patient families have consented, and the local team has been able to collect continuous EEG, blood pressure with arterial wave forms, EKG activity and oxygen saturations. 

​Recently, the London team presented an abstract of their progress to date at the Canadian Neurological Sciences Congress in Quebec City (read the abstract here). Researcher Loretta Norton says the poster generated a lot of interest amongst neurologists at the congress, and she is looking forward to getting additional feedback from a broader audience, including from any interested DePPaRT investigators.

Congratulations Loretta and the London team on a great poster presentation and for leading this important neurological aspect of DePPaRT!
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    Author

    Amanda van Beinum
    Research Associate

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